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Firstly, mice with conditional deletion of Chrm1, the gene encoding M1R (a negative regulator of OPC differentiation), in OPCs were crossed with APP/PS1 mice to generate APP/PS1/M1R cKO mice

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Size:22 lb / 10 kg

At NTP-7 Level 3 we observed area of fronto-parietal cortex, hippocampus, thalamus and hypothalamus