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Semaglutide, a glucagon-like peptide-1 (GLP-1) receptor agonist, has well-established weight-loss benefits. Cagrilintide, a long-acting analogue of the satiety hormone amylin, has shown promise for weight loss in early trials. The potential benefit

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But those studies, McGuire says, don’t have a lot of evidence behind them, and if you look on Reddit or other places where people are talking about it, he says, it appears that most people are recommending repeated doses